If you leave your computer running on a 24/7 basis you might be interested in determining the amount of uptime that has accumulated since the last reboot.
Neat little trick to force the preview images of running programs in Windows 7 taskbar or a so called Aero Peek, to show instantly with no delay at all.
Some installations or settings changes require you to restart your computer. In most cases you don't need to actually reboot it, you only need to restart the explorer.exe process.
If you can't copy files that are bigger than 2 or 4 GB, usually HD movies and such, on to your USB key, it's usually due to the file system the USB key is formatted to.